Starred review from April 4, 2011
Patchett (Bel Canto) is a master storyteller who has an entertaining habit of dropping ordinary people into extraordinary and exotic circumstances to see what they're made of. In this expansive page-turner, Marina Singh, a big pharma researcher, is sent by her married boss/lover to the deepest, darkest corner of the Amazon to investigate the death of her colleague, Anders Eckman, who had been dispatched to check on the progress of the incommunicado Dr. Annick Swenson, a rogue scientist on the cusp of developing a fertility drug that could rock the medical profession (and reap enormous profits). After arriving in Manaus, Marina travels into her own heart of darkness, finding Dr. Swenson's camp among the Lakashi, a gentle but enigmatic tribe whose women go on bearing children until the end of their lives. As Marina settles in, she goes native, losing everything she had held on to so dearly in her prescribed Midwestern life, shedding clothing, technology, old loves, and modern medicine in order to find herself. Patchett's fluid prose dissolves in the suspense of this out-there adventure, a juggernaut of a trip to the crossroads of science, ethics, and commerce that readers will hate to see end.

August 1, 2014

Deep in the Amazon jungle, a research scientist confronts her past and her own mortality, with life-altering consequences. Narrated by Hope Davis. (LJ 10/1/11)

Copyright 2014 Library Journal, LLC Used with permission.

February 1, 2011
A pharmacologist travels into the Amazonian heart of darkness in this spellbinder from bestselling author Patchett (Run, 2007, etc.).

Marina Singh is dispatched from the Vogel pharmaceutical company to Brazil to find out what happened to her colleague Anders Eckman, whose death was announced in a curt letter from Annick Swenson. Anders had been sent to check on Dr. Swenson's top-secret research project among the Lakashi tribe, whose women continue to bear children into their 60s and 70s. If a fertility drug can be derived from whatever these women are ingesting, the potential rewards are so enormous that Swenson has been pursuing her work for years with scant oversight from Vogel; the company doesn't even know exactly where she is in the Amazon. Marina, who went into pharmacology after making a disastrous mistake as an obstetrics resident under Dr. Swenson's supervision, really doesn't want to see this intimidating woman again, but she feels an obligation to her friend Anders and his grief-stricken wife. So she goes to Manaus, seeking clues to Dr. Swenson's location in the jungle. By the time the doctor turns up unexpectedly, Patchett has skillfully crafted a portrait from Marina's memories and subordinates' comments that gives Swenson the dark eminence of Joseph Conrad's Mr. Kurtz. Engaged like Kurtz in godlike pursuits among the natives, Swenson is performing some highly unorthodox experiments, the ramifications of which have even more possibilities than Vogel imagines. Indeed, the multiple and highly dramatic developments that ensue once Marina gets to the Lakashi village might seem ridiculous, if Patchett had not created such credible characters and a dreamlike milieu in which anything seems possible. Nail-biting action scenes include a young boy's near-mortal crushing by a 15-foot anaconda, whose head Marina lops off with a machete; they're balanced by contemplative moments that give this gripping novel spiritual and metaphysical depth, right down to the final startling plot twist.

Thrilling, disturbing and moving in equal measures--even better than Patchett's breakthrough Bel Canto (2001).

(COPYRIGHT (2011) KIRKUS REVIEWS/NIELSEN BUSINESS MEDIA, INC. ALL RIGHTS RESERVED.)

February 1, 2011
Marina Singh gave up a career as a doctor after botching an emergency delivery as an intern, opting instead for the more orderly world of research for a pharmaceutical company. When office colleague Anders Eckman, sent to the Amazon to check on the work of a field team, is reported dead, Marina is asked by her companys CEO to complete Anders task and to locate his body. What Marina finds in the sweltering, insect-infested jungles of the Amazon shakes her to her core. For the team is headed by esteemed scientist Annick Swenson, the woman who oversaw Marinas residency and who is now intent on keeping the teams progress on a miracle drug completely under wraps. Marinas jungle odyssey includes exotic encounters with cannibals and snakes, a knotty ethical dilemma about the basic tenets of scientific research, and joyous interactions with the exuberant people of the Lakashi tribe, who live on the compound. In fluid and remarkably atmospheric prose, Patchett captures not only the sights and sounds of the chaotic jungle environment but also the struggle and sacrifice of dedicated scientists. HIGH-DEMAND BACKSTORY: The award-winning, New York Times best-selling authors latest novel is being supported with an author tour, a national advertising campaign, blogger outreach, and a reading-group guide.(Reprinted with permission of Booklist, copyright 2011, American Library Association.)

Starred review from April 1, 2011

In this superbly rendered novel, Patchett (Run) takes the reader into the primitive world of the Amazon in Brazil. Pharmacologist Marina Singh from Minnesota works for the pharmaceutical company Vogel. Her colleague Anders Eckman dies in the jungle while trying to locate Dr. Annick Swenson, who has been working on a fertility drug for Vogel by studying the Lakashi people, whose women bear children into old age. Marina's journey to the Amazon to find the uncommunicative and intimidating Dr. Swenson and to discover the details of Anders's death is fraught with poisonous snakes and poisonous memories, malarial mosquitoes and sickening losses, but her time among the Lakashi tribe is transformative. VERDICT Not a sentimental view of a primitive people, Patchett's portrayal is as wonderful as it is frightening and foreign. Patchett exhibits an extraordinary ability to bring the horrors and the wonders of the Amazon jungle to life, and her singular characters are wonderfully drawn. Readers who enjoy exotic locales will especially be interested, but all will find this story powerful and captivating. [See Prepub Alert, 11/29/10.]--Joy Humphrey, Pepperdine Univ. Law Lib., Malibu, CA

Copyright 2011 Library Journal, LLC Used with permission.

January 1, 2011

Marina Singh, who's given up her medical practice for the relative quiet of pharmaceutical research, finds her world upturned when she's suddenly sent to the Amazon. A field team there, working on a new drug, has been unresponsive for two years, and Marina's colleague Anders, who has gone to investigate, is reported dead. An adventurous story of science and responsibility from the ever-popular Patchett, who's being rewarded with a one-day laydown on June 7, a 300,000-copy first printing, and a 12-city tour. Buy multiples.

Copyright 2011 Library Journal, LLC Used with permission.